Home   chapter home   jobs   conferences   fellowships   books advertisement soft tissue tumors fibroblastic / myofibroblastic tumors hemangiopericytoma reviewer: komal arora, m. D. (see reviewers page) revised: 21 july 2012, last major update july 2012 copyright: (c) 2003-2012, pathologyoutlines. Com, inc. General ========================================================================= ● controversial entity ● rare lesions similar to cellular solitary fibrous tumor - may not actually differ ● diagnosis of exclusion ( histopathology 2006;48:63 ) ● historically defined as lesions with thin walled, branching vascular pattern, although this pattern is common in many lesions ● probably not a lesion of pericytes, except at sinonasal location ● see myofibroma / myofibromatosis for infantile lesions ● see also discussions in these chapters: bone , breast , cns , heart , nasal cavity , thyroid gland epidemiology ========================================================================= ● middle aged adults, more common in women ● most common in deep soft tissue, particularly pelvic retroperitoneum, also limb or limb girdles and head and neck ● occasionally associated with hypoglycemia ( j clin endocrinol metab 1996;81:919 ) ● 5 year survival was 86% in 2002 ( cancer 2002;95:1746 ) ● 70% have benign behavior ● poor prognostic factors may be 4+ mitotic figures/10 hpf, necrosis, nuclear pleomorphism with size > 5 cm case reports ========================================================================= ● 54 year old woman ( acta otorhinolaryngol ital 2011;31:194 ● 61 year old man with omental tumor with metastases ( world j surg oncol 2007;5:63 ) ● 70 year old man with spontaneous rupture of cystic splenic tumor ( int j emerg med 2011;4:13 ) gross description ========================================================================= ● well circumscribed, yellow-tan cut surface, fleshy or spongy with hemorrhage but no necrosis, up to 15 cm gross images =========================================================================     encapsulated omental tumor patient with 3 tumors: (a) greater omentum tumor (under forceps) (b) small jejunal tumor (c) retroperitoneal tumor with portions of diaphragm and liver micro description ========================================================================= ● uniformly cellular (similar to cellular areas of solitary fibrous tumor) with numerous, variably ectatic or compressed, thin walled branching vessels with staghorn configuration ● tumor cells are spindled to round with small amounts of pale or eosinophilic cytoplasm, indistinct margins, bland vesicular nuclei ● stromal hyalinization. viagra for sale buying viagra medicaresupplementspecialists.com/pfz-100-mg-generic-viagra-np/ viagra without a doctor prescription generic viagra online generic viagra online viagra for sale viagra online buy generic viagra cheap viagra viagra dosage women